How heart cells help form new blood vessels after injury
Official title: Regulation of angiogenesis by cardiac fibroblasts
Funded at University of California Los Angeles · NIH-11048052 · Data updated 2026-11-12
This study is looking at how certain heart cells help create new blood vessels after a heart injury, like a heart attack, to find better ways to help patients heal and recover.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | February 1, 2025 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $740,037 |
| NIH project number | 1R01HL172852-01A1 |
| Project ID | NIH-11048052 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who have experienced a myocardial infarction or heart attack.
✕Less likely to help
Patients with stable heart conditions who have not experienced a recent heart attack may not benefit from this research.
What this research studies
This research investigates the role of cardiac fibroblasts, a type of heart cell, in the formation of new blood vessels following a heart injury, such as a heart attack. The study focuses on how these cells release specific factors that can either promote or inhibit blood vessel growth, which is crucial for heart repair. By understanding the timing and nature of these signals, the research aims to uncover new therapeutic strategies to enhance recovery after myocardial infarction. Patients may benefit from insights that could lead to improved treatments for heart conditions.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance heart repair and improve outcomes for patients recovering from heart attacks.
How similar studies have gone: Previous research has shown promising results in understanding the role of fibroblasts in heart repair, suggesting that this approach could lead to significant advancements in treatment.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Quijada, Pearl Jennine — University of California Los Angeles
- Study coordinator: Quijada, Pearl Jennine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.