How health conditions affect the absorption of vitamin B1 in the intestines
Effect of Pathophysiological Conditions on Intestinal Absorption of Free Thiamin
This study is looking at how different health issues affect your body's ability to take in vitamin B1 from food and gut bacteria, especially for people with conditions like inflammatory bowel disease and chronic alcoholism, to help understand why some might not get enough of this important vitamin.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Long Beach, United States) |
| Project ID | NIH-10911020 on NIH RePORTER |
What this research studies
This research investigates how various health conditions influence the body's ability to absorb vitamin B1, also known as thiamin, from both dietary sources and those produced by gut bacteria. The study focuses on the mechanisms of absorption in the small and large intestines, particularly looking at the roles of specific transport proteins involved in this process. By understanding these mechanisms, the research aims to identify how deficiencies in vitamin B1 can occur in conditions like inflammatory bowel disease and chronic alcoholism, which can lead to significant health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions that affect intestinal absorption, such as inflammatory bowel disease or chronic alcoholism.
Not a fit: Patients who do not have any gastrointestinal disorders or issues related to vitamin B1 absorption may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from vitamin B1 deficiencies, enhancing their overall health and quality of life.
How similar studies have performed: Previous research has shown promising results in understanding vitamin absorption mechanisms, indicating that this approach has potential for success.
Where this research is happening
Long Beach, United States
- Veterans Health Administration — Long Beach, United States (Active)
Researchers
- Principal investigator: Said, Hamid M — Veterans Health Administration
- Study coordinator: Said, Hamid M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.