How harmful algae in the air can affect lung health

Atmospheric transformation of harmful cyanobacterial algae and novel mechanisms of pulmonary toxicity

['FUNDING_R21'] · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · NIH-10948382

This study is looking at how breathing in toxins from harmful algae can affect lung health, especially for people living near lakes or rivers with these algae, to help us understand the risks better.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA (nih funded)
Locations1 site (COLUMBIA, UNITED STATES)
Trial IDNIH-10948382 on ClinicalTrials.gov

What this research studies

This research investigates the effects of harmful algal blooms (HABs) on respiratory health, particularly focusing on the inhalation of toxins produced by cyanobacteria. It aims to understand how these toxins transform in the atmosphere and their potential subacute health implications, especially for individuals living near affected water bodies. By studying animal and cell models, the research seeks to uncover the immune responses triggered by inhaled algal toxins, which have not been thoroughly explored in previous studies. The findings could provide insights into the risks associated with airborne exposure to these harmful algae.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living near freshwater bodies affected by harmful algal blooms, particularly those experiencing respiratory symptoms.

Not a fit: Patients who do not live in proximity to freshwater bodies with harmful algal blooms may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and management of respiratory health risks associated with harmful algal blooms.

How similar studies have performed: While there is limited research on the inhalation of algal toxins, studies have shown significant health impacts from waterborne exposure, indicating a need for further investigation into airborne exposure.

Where this research is happening

COLUMBIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.