How Gut Microbes Control Vitamin A and Immune Health
Microbial Regulation of Retinol Transport and its Role in Intestinal Immunity
This research explores how the bacteria in our gut help our bodies use vitamin A to build strong immune responses in the intestines.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-11121919 on NIH RePORTER |
What this research studies
This research explores how the bacteria in our gut influence how our bodies use vitamin A, a crucial nutrient for a healthy immune system. Specifically, it focuses on how a protein called SAA helps deliver vitamin A to immune cells in the intestines. A strong immune response in the gut is vital for fighting off infections and preventing diseases. By understanding these processes, we hope to learn more about how to maintain a healthy gut and prevent immune-related conditions.
Who could benefit from this research
Good fit: Patients with intestinal immune disorders or those prone to gut infections might find this research particularly relevant.
Not a fit: Patients whose conditions are unrelated to gut immunity or vitamin A metabolism may not directly benefit from this specific research.
Why it matters
Potential benefit: This work could lead to new ways to improve gut health and strengthen the immune system, potentially helping patients with intestinal diseases or infections.
How similar studies have performed: Previous work by this team has already identified a key mechanism for vitamin A delivery to immune cells, suggesting a strong foundation for this continued research.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Hooper, Lora V — Ut Southwestern Medical Center
- Study coordinator: Hooper, Lora V
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.