How gut cells affect metabolism and appetite control
Role of colonic enteroendocrine cells in metabolic control
This study is looking at special cells in the colon that help control hunger and metabolism, using mice to see how these cells affect weight and health, which could help people understand how gut health plays a role in managing weight and metabolic issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-11105926 on NIH RePORTER |
What this research studies
This research investigates the role of specialized cells in the colon that produce hormones influencing metabolism and appetite. By studying mice with a deficiency in these cells, researchers aim to understand how they contribute to metabolic balance and the regulation of body weight. The study focuses on the interactions between these cells, the gut microbiota, and their overall impact on health. Patients may benefit from insights into how gut health can affect weight management and metabolic disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or metabolic disorders, particularly those interested in the role of gut health in weight management.
Not a fit: Patients who do not have metabolic issues or are not interested in the relationship between gut health and metabolism may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing obesity and metabolic diseases through gut hormone regulation.
How similar studies have performed: Previous research has shown promising results in understanding the role of gut hormones in metabolism, suggesting that this approach could yield valuable insights.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Burstein, Ezra — Ut Southwestern Medical Center
- Study coordinator: Burstein, Ezra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.