How gut bacteria influence brain cell function
Microbial Regulation of Microglial Function
This study is looking at how the bacteria in our bodies might influence brain cells that help with learning and emotions, to better understand how gut health can affect our mental well-being.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10894682 on NIH RePORTER |
What this research studies
This research investigates how the microbiome, the community of bacteria in our bodies, affects the development and function of brain cells called microglia. By studying the interactions between these bacteria and microglia, the research aims to understand how these relationships influence brain health and behavior. The approach includes experiments that analyze how signals from bacteria can change microglial activity and how this, in turn, affects brain processes related to learning and emotional responses. The findings could provide insights into the role of gut health in mental health and cognitive function.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who may be experiencing cognitive disturbances or affective disorders.
Not a fit: Patients with neurological conditions unrelated to microbiome interactions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving mental health and cognitive function by targeting the microbiome.
How similar studies have performed: Previous studies have shown promising results in understanding the link between the microbiome and neuropsychiatric disorders, suggesting that this research builds on established findings.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Parkhurst, Christopher Neal — Weill Medical Coll of Cornell Univ
- Study coordinator: Parkhurst, Christopher Neal
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.