How gut bacteria communicate with the brain and affect blood pressure.
Bacterial extracellular vesicles in microbiota-brain communication and hypertension
['FUNDING_R01'] · BAYLOR COLLEGE OF MEDICINE · NIH-11020038
This study is looking at how the bacteria in your gut might influence high blood pressure by sending signals to your brain, and it hopes to find new ways to improve heart health for people dealing with hypertension.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11020038 on ClinicalTrials.gov |
What this research studies
This research investigates how changes in gut bacteria can lead to high blood pressure through a communication system between the gut and the brain. It focuses on the role of bacterial extracellular vesicles, which are tiny particles released by bacteria, in causing inflammation that may affect blood pressure regulation. By studying these mechanisms, the research aims to uncover new pathways that link gut health to cardiovascular health, potentially leading to innovative treatments for hypertension.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with hypertension or those at risk of developing high blood pressure.
Not a fit: Patients without hypertension or those with conditions unrelated to gut health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating high blood pressure by targeting gut bacteria.
How similar studies have performed: Other research has shown promising results in understanding the gut-brain connection and its impact on various health conditions, suggesting that this approach could yield valuable insights.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DURGAN, DAVID J — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: DURGAN, DAVID J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.