How gut bacteria affect colon health and cancer risk
The gut microbiome, interactions with primed colon states, and effects on adenoma formation and progression
This study is looking at how the bacteria in your gut might affect the growth of adenomas, which can lead to colon cancer, and it’s inviting patients to help by sharing samples or information to find new ways to prevent this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11187500 on NIH RePORTER |
What this research studies
This research investigates the role of the gut microbiome in the development and progression of adenomas, which are precursors to colon cancer. By examining how interactions with specific colon states influence these processes, the study aims to uncover potential mechanisms that could lead to new prevention strategies. Patients may be involved in providing samples or data that help researchers understand these interactions better. The approach combines microbiome analysis with clinical observations to draw connections between gut health and cancer risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a history of adenomas or those at high risk for colon cancer.
Not a fit: Patients without any history of colon issues or those not at risk for adenoma formation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing colon cancer by targeting gut microbiome health.
How similar studies have performed: Other research has shown promising results in understanding the gut microbiome's role in cancer, suggesting this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Dey, Neelendu — Fred Hutchinson Cancer Center
- Study coordinator: Dey, Neelendu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.