How gut bacteria affect bone growth and health
Role of Complement in Commensal Microbiota Actions Regulating Sketal Maturation
This study is looking at how the bacteria in your gut might help keep your bones healthy after puberty by affecting your immune system, and it aims to find new ways to understand and treat bone-related issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ralph H Johnson VA Medical Center NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project ID | NIH-10911033 on NIH RePORTER |
What this research studies
This research investigates the role of gut microbiota in regulating bone health and development, particularly after puberty. It focuses on how these bacteria influence immune responses that affect bone-forming and bone-resorbing cells, which are crucial for maintaining bone density. By studying the interactions between gut bacteria and the immune system, the research aims to uncover mechanisms that could lead to better understanding and treatment of bone-related conditions. The study will utilize various models to explore these complex relationships over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals under 21 years old who are experiencing issues related to bone health or development.
Not a fit: Patients over 21 years old or those without bone health concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving bone health and preventing conditions like osteoporosis.
How similar studies have performed: Preliminary findings suggest that similar approaches have shown promise in understanding the relationship between gut microbiota and bone health, indicating potential for success.
Where this research is happening
Charleston, United States
- Ralph H Johnson VA Medical Center — Charleston, United States (Active)
Researchers
- Principal investigator: Hathaway-Schrader, Jessica Diann — Ralph H Johnson VA Medical Center
- Study coordinator: Hathaway-Schrader, Jessica Diann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.