How gut bacteria affect aging and inflammation in adults

The Microbiome and Biological Aging in the Add Health Study

NIH-funded research University of Colorado · NIH-10819485

This study is looking at how the bacteria in our gut might affect how we age and deal with inflammation, especially in adults, to help find ways to improve health as we get older.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado NIH-funded
Lab location1 site (Boulder, UNITED STATES)
Project IDNIH-10819485 on NIH RePORTER

What this research studies

This research investigates the relationship between gut microbiota and biological aging, particularly focusing on inflammation and immune system changes in adults. By analyzing data from a large national study, the researchers aim to understand how variations in gut bacteria may contribute to differences in aging and inflammation among individuals. The study will collect and analyze samples from participants to explore these connections and identify potential intervention points for improving health outcomes. This research is particularly relevant for understanding aging processes before individuals reach older age.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are interested in understanding the impact of gut health on aging.

Not a fit: Patients who are not adults or those with specific gastrointestinal disorders that may confound microbiome analysis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing age-related diseases by targeting gut microbiota.

How similar studies have performed: Previous studies have shown promising results linking gut microbiota to inflammation and aging, suggesting that this research builds on a foundation of emerging evidence.

Where this research is happening

Boulder, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.