How ghrelin signaling affects fat tissue and metabolism
Crosstalk between sensory ghrelin signaling and adipose tissue sympathetic outflow regulates metabolic homeostasis
['FUNDING_R01'] · GEORGIA STATE UNIVERSITY · NIH-10555316
This study is looking at how a hormone called ghrelin, which comes from your stomach, affects how your body uses energy and stores fat, especially when you're hungry or cold, to find new ways to help manage obesity and related health issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGIA STATE UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-10555316 on ClinicalTrials.gov |
What this research studies
This research investigates the role of ghrelin, a hormone produced in the stomach, in regulating energy balance and metabolism, particularly focusing on its effects on sensory neurons and adipose tissue. The study aims to understand how ghrelin signaling influences energy expenditure and fat storage, especially during conditions like food deprivation and cold exposure. By examining the interactions between ghrelin receptors in sensory neurons and adipose tissue, the research seeks to uncover new pathways that could help manage obesity and related metabolic diseases. Patients may benefit from insights that could lead to novel treatments for obesity and its complications.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or metabolic diseases such as type 2 diabetes and cardiovascular conditions.
Not a fit: Patients who are not affected by obesity or metabolic disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating obesity and related metabolic disorders.
How similar studies have performed: Other research has shown promising results in understanding the role of ghrelin in metabolism, indicating that this approach may lead to significant advancements.
Where this research is happening
ATLANTA, UNITED STATES
- GEORGIA STATE UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: XUE, BINGZHONG — GEORGIA STATE UNIVERSITY
- Study coordinator: XUE, BINGZHONG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.