How gestational diabetes and depression affect mothers and their children's brain development
Official title: Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype
Funded at New York University School of Medicine · NIH-10922858 · Data updated 2026-11-12
This study is looking at how gestational diabetes and prenatal depression can affect a mom's mental health and the brain development of her baby, with the goal of finding ways to better support moms and their little ones.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $246,509 |
| NIH project number | 5R00HD103910-04 |
| Project ID | NIH-10922858 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant women diagnosed with gestational diabetes or experiencing prenatal depression, particularly those from ethnic and racial minority groups.
✕Less likely to help
Patients who are not pregnant or do not have gestational diabetes or prenatal depression may not benefit from this research.
What this research studies
This research investigates the connections between gestational diabetes mellitus (GDM) and prenatal depression, focusing on how these conditions impact maternal mental health and the brain development of newborns and toddlers. The study aims to identify specific pathways that link these maternal health issues to potential neurodevelopmental challenges in children, such as social-emotional and attentional deficits. By examining these relationships, the research seeks to provide insights that could lead to improved support for affected mothers and their children.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and interventions for mothers with GDM and depression, ultimately improving the developmental outcomes for their children.
How similar studies have gone: Previous research has shown significant associations between maternal health conditions like GDM and depression and adverse outcomes in offspring, indicating that this approach is grounded in established findings.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Shuffrey, Lauren Christine — New York University School of Medicine
- Study coordinator: Shuffrey, Lauren Christine
Related research
Other NIH-funded projects on the same topics.
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Understanding how gestational diabetes and depression during pregnancy affect mothers and their children
This project explores how gestational diabetes and depression during pregnancy might influence a mother's mental health after birth and her child's brain development.
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The effects of gestational diabetes and maternal depression on child development
This study looks at how having gestational diabetes and feeling depressed during pregnancy might affect how children develop, and it’s for moms-to-be who want to understand how their health can impact their little ones.
-
In Vivo Look at Placental Blood Flow in Gestational Diabetes
A non-invasive MRI study in pregnant people with gestational diabetes and those without will map how placental blood vessels work and relate to baby outcomes.
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Decoding how gestational diabetes links to future coronary artery disease
A study using health records and big data to understand why women who had gestational diabetes later face heart disease, with the goal of guiding prevention.
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Better Blood Sugar Goals for Pregnant Women with Gestational Diabetes Who Are Overweight or Obese
This project looks at whether stricter blood sugar goals can help pregnant women who have gestational diabetes and are also overweight or obese have healthier pregnancies and babies.
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Understanding how gestational diabetes develops during pregnancy
This study is looking at how the body's insulin-producing cells change in pregnant women to better understand gestational diabetes and help improve diabetes care for moms both during and after pregnancy.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.