How genetics influence the benefits of a specific diet for brain health
Genetic modifiers of the Mediterranean-DASH diet Intervention for Neurodegenerative Delay (MIND) response
This study is looking at how your genes might influence how well you respond to the MIND diet, which is meant to help slow down memory loss and lower the risk of Alzheimer's, and we're inviting people to join in by sharing their diet habits and getting some genetic testing done.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10853102 on NIH RePORTER |
What this research studies
This research investigates how genetic differences affect individual responses to the Mediterranean-DASH Diet Intervention for Neurodegenerative Delay (MIND), which is designed to slow cognitive decline and reduce the risk of Alzheimer's disease. By analyzing genetic information alongside dietary adherence, the study aims to identify which individuals may benefit the most from this diet. The approach combines data from an ongoing MIND trial with existing community and population-based data to explore the interplay between genetics and diet. Patients may be asked to participate in dietary assessments and genetic testing to help determine their potential response to the MIND diet.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease or those experiencing cognitive decline who are interested in dietary interventions.
Not a fit: Patients who do not have genetic predispositions related to Alzheimer's disease or who are not interested in dietary changes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could help identify specific dietary recommendations tailored to individuals based on their genetic makeup, potentially improving cognitive health outcomes.
How similar studies have performed: Previous research has shown promising results in dietary interventions for cognitive health, suggesting that this approach may yield valuable insights.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Cornelis, Marilyn C — Northwestern University at Chicago
- Study coordinator: Cornelis, Marilyn C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.