How genetics and medication affect cognitive impairment in people with HIV
Genetic Predisposition and Pharmacogenomics of HIV-Associated Cognitive Impairment
['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10712363
This study is looking at how your genes might affect how well HIV treatment works for preventing memory and thinking problems, and it's for people living with HIV who want to understand more about their health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10712363 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between genetic factors and the effectiveness of antiretroviral therapy (ART) in managing cognitive impairment associated with HIV. It utilizes a large cohort of people living with HIV to analyze how genetic predispositions influence the risk of developing neurocognitive deficits, including dementia. By understanding these interactions, the research aims to improve treatment strategies and reduce the incidence of cognitive decline in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are experiencing cognitive impairment or are at risk for developing such impairments.
Not a fit: Patients who are not living with HIV or who do not have cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized treatment plans that enhance cognitive health for individuals living with HIV.
How similar studies have performed: Previous research has shown promising results in understanding the genetic factors influencing treatment responses in chronic diseases, suggesting potential for success in this area as well.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PETER, INGA — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: PETER, INGA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome, Acquired Immuno-Deficiency Syndrome, Acquired Immunologic Deficiency Syndrome, Acquired Immunodeficiency Syndrome, Alzheimer disease dementia