How genetics and diet affect metabolism and health
Genetic Control of Metabolic Flux in Response to Diet
This study is looking at how our genes might affect how we respond to different diets, especially when it comes to our metabolism and health, using mice to find out which genes work with diet and gut bacteria to influence things like blood sugar and weight, so we can eventually give better diet advice for people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10861831 on NIH RePORTER |
What this research studies
This research investigates how genetic differences influence the way individuals respond to various diets, particularly in terms of metabolic health. By using a genetically diverse population of mice, the study aims to identify specific genes that interact with diet and the gut microbiome to impact conditions like glucose tolerance and body weight. The researchers will test two different diets and measure various metabolic outcomes, providing insights that could help tailor dietary recommendations for better health outcomes in humans.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with metabolic disorders or those interested in understanding how their genetics may affect their dietary needs.
Not a fit: Patients who do not have metabolic issues or are not interested in dietary interventions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized dietary recommendations that improve metabolic health and reduce the risk of related diseases.
How similar studies have performed: Previous research has shown that genetic factors significantly influence dietary responses, suggesting that this approach could yield valuable insights.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Attie, Alan D — University of Wisconsin-Madison
- Study coordinator: Attie, Alan D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.