NIH-funded research NIH-funded research

How genetics and brain function affect learning differences in autism and other conditions

Official title: Genetic and Neural Sources of Individual Differences in Goal-directed Learning in Health and Disease

Funded at Boston University (Charles River Campus) · NIH-11074789 · Data updated 2026-11-12

This study is looking at how our genes might affect learning abilities, especially for people with Autism Spectrum Disorder and Intellectual Disabilities, to help us find better ways to support them in their learning journeys.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBoston University (Charles River Campus)
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2026
Funding year2024
Award (this year)$49,625
NIH project number1F99NS141346-01
Project IDNIH-11074789 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals aged 12-20 diagnosed with Autism Spectrum Disorder or related cognitive challenges.

Less likely to help

Patients outside the age range of 12-20 or those without learning differences may not benefit from this research.

What this research studies

This research investigates how genetic variations influence learning abilities in individuals, particularly focusing on those with Autism Spectrum Disorder (ASD) and Intellectual Disabilities. By studying the genetic and neural mechanisms behind these differences, the project aims to uncover how specific genes affect brain function and learning processes. The research utilizes advanced techniques like spatial transcriptomics and calcium imaging to analyze brain cells and their roles in learning. This could lead to a better understanding of how to support individuals with learning challenges.

Why it matters

Potential benefit: If successful, this research could lead to targeted interventions that enhance learning capabilities in individuals with autism and related disorders.

How similar studies have gone: Previous research has shown promising results in understanding genetic influences on learning, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Boston University (Charles River Campus)
    Boston, United States
    Active

Researchers

  • Principal investigator: Carey, Alanna — Boston University (Charles River Campus)
  • Study coordinator: Carey, Alanna

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.