How genetics affect cancer risk and outcomes in African American adults
Genetic Variation in Cancer Risk and Outcomes in African Americans
['FUNDING_P01'] · WAYNE STATE UNIVERSITY · NIH-11287877
This project offers culturally tailored genetic education and online counseling to help African American adults understand cancer-related genetic risk and get recommended genetic testing.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WAYNE STATE UNIVERSITY (nih funded) |
| Locations | 1 site (DETROIT, UNITED STATES) |
| Trial ID | NIH-11287877 on ClinicalTrials.gov |
What this research studies
You would be invited through a community partnership in Detroit to help adapt educational materials about genetic cancer risk for African American adults. The research team will work with the Genomics Research Action Council to tailor messaging and genetic counseling content to address medical mistrust and low genomic literacy. They will develop and deliver online genetic counseling information and tools to reduce barriers like cost, transportation, and limited local services. The intervention will be guided by the ORBIT model and refined with community feedback before wider use.
Who could benefit from this research
Good fit: Ideal participants are African American adults (21+) who are at risk for hereditary cancer, have a cancer diagnosis, or are interested in genetic testing but face barriers to traditional counseling.
Not a fit: People under 21, non–African American individuals, or those without reliable internet access who cannot use online counseling may not benefit from this project.
Why it matters
Potential benefit: If successful, this work could increase uptake of guideline-recommended genetic testing among African American adults, supporting earlier risk detection and more personalized care.
How similar studies have performed: Previous culturally tailored education and tele-genetics programs have shown promise for improving counseling and testing uptake, but large-scale efforts focused on African American communities are still limited.
Where this research is happening
DETROIT, UNITED STATES
- WAYNE STATE UNIVERSITY — DETROIT, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HARPER, FELICITY — WAYNE STATE UNIVERSITY
- Study coordinator: HARPER, FELICITY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.