How genetic mutations influence evolution
Structural variants and the locus of evolution
['FUNDING_OTHER'] · FLORIDA INTERNATIONAL UNIVERSITY · NIH-10850709
This study is looking at how certain changes in our DNA can affect evolution and genetic diversity, which could help people understand genetic disorders better and how they change over time.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FLORIDA INTERNATIONAL UNIVERSITY (nih funded) |
| Locations | 1 site (MIAMI, UNITED STATES) |
| Trial ID | NIH-10850709 on ClinicalTrials.gov |
What this research studies
This research investigates the role of genetic mutations, particularly structural variants, in the process of evolution. It focuses on understanding how these mutations, which can include duplications and deletions of DNA segments, affect genetic diversity and population dynamics. By utilizing advanced DNA sequencing technologies, the study aims to uncover the mechanisms behind these mutations and their long-term impacts on genomes. Patients may benefit from insights into genetic disorders linked to these mutations and how they evolve over time.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit include individuals with genetic disorders or those interested in genetic research related to evolution.
Not a fit: Patients with conditions unrelated to genetic mutations or evolution may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic disorders and lead to improved diagnostic and therapeutic strategies.
How similar studies have performed: While the focus on structural variants in evolution is relatively novel, previous studies have shown success in understanding single nucleotide polymorphisms and their impact on genetic diversity.
Where this research is happening
MIAMI, UNITED STATES
- FLORIDA INTERNATIONAL UNIVERSITY — MIAMI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FIERST, JANNA LYNN — FLORIDA INTERNATIONAL UNIVERSITY
- Study coordinator: FIERST, JANNA LYNN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Disease