How genes are regulated during development
Genetic and epigenetic mechanisms of developmental gene regulation
This study is looking at how our genes help cells become different types, and how problems in this process can lead to diseases, with the hope of finding new ways to treat those conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11090394 on NIH RePORTER |
What this research studies
This research investigates the genetic and epigenetic mechanisms that control how cells develop and differentiate into specific cell types. By studying the processes that determine cell identity, the research aims to understand how disruptions in these mechanisms can lead to diseases. The approach involves examining how DNA is packaged and modified, which affects gene expression and cellular behavior. Insights gained from this research could help identify potential therapeutic targets for diseases caused by developmental errors.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to developmental disorders or diseases caused by cell identity disruptions.
Not a fit: Patients with fully developed and stable cell identities, without any associated developmental disorders, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases linked to improper cell differentiation.
How similar studies have performed: Other research has shown success in understanding gene regulation mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Mckay, Daniel J — Univ of North Carolina Chapel Hill
- Study coordinator: Mckay, Daniel J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.