How gender affects asthma severity
Official title: Gender and Asthma
Funded at Mayo Clinic Arizona · NIH-11002000 · Data updated 2026-11-12
This study is looking at how asthma affects men and women differently, especially how hormones might play a role, to help us understand why some people have more severe asthma and how we can improve their treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $363,443 |
| NIH project number | 5R01HL161674-03 |
| Project ID | NIH-11002000 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults over 21 years old, particularly women experiencing severe asthma symptoms.
✕Less likely to help
Patients with asthma who are under 21 years old or those whose asthma is not influenced by hormonal factors may not benefit from this research.
What this research studies
This research investigates the differences in asthma severity between genders, particularly focusing on how sex hormones influence these differences. By analyzing data from well-characterized asthma cohorts and large databases, the study aims to uncover the genetic risks and biological pathways that contribute to severe asthma in both men and women. The research will explore the correlation between hormone levels and lung function, providing insights into how these factors may affect airway inflammation and asthma outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for asthma based on gender-specific factors.
How similar studies have gone: Previous research has shown promising results in understanding gender differences in asthma, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Mayo Clinic Arizona
Scottsdale, United States Active
Researchers
- Principal investigator: Zein, Joe — Mayo Clinic Arizona
- Study coordinator: Zein, Joe
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.