How gender affects asthma severity
Gender and Asthma
['FUNDING_R01'] · MAYO CLINIC ARIZONA · NIH-11002000
This study is looking at how asthma affects men and women differently, especially how hormones might play a role, to help us understand why some people have more severe asthma and how we can improve their treatment.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC ARIZONA (nih funded) |
| Locations | 1 site (SCOTTSDALE, UNITED STATES) |
| Trial ID | NIH-11002000 on ClinicalTrials.gov |
What this research studies
This research investigates the differences in asthma severity between genders, particularly focusing on how sex hormones influence these differences. By analyzing data from well-characterized asthma cohorts and large databases, the study aims to uncover the genetic risks and biological pathways that contribute to severe asthma in both men and women. The research will explore the correlation between hormone levels and lung function, providing insights into how these factors may affect airway inflammation and asthma outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over 21 years old, particularly women experiencing severe asthma symptoms.
Not a fit: Patients with asthma who are under 21 years old or those whose asthma is not influenced by hormonal factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for asthma based on gender-specific factors.
How similar studies have performed: Previous research has shown promising results in understanding gender differences in asthma, suggesting that this approach could yield valuable insights.
Where this research is happening
SCOTTSDALE, UNITED STATES
- MAYO CLINIC ARIZONA — SCOTTSDALE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZEIN, JOE — MAYO CLINIC ARIZONA
- Study coordinator: ZEIN, JOE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.