How gastric bypass surgery affects mothers and their children's health
The impact of gastric bypass on maternal and offspring metabolic health
This study looks at how weight loss surgery called Roux-en-Y gastric bypass can help moms and their kids by exploring if it reduces the chances of children becoming obese when their mothers were overweight during pregnancy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-10557865 on NIH RePORTER |
What this research studies
This research investigates the effects of Roux-en-Y gastric bypass (RYGB) surgery on the health of mothers and their offspring. It aims to understand how maternal obesity during pregnancy influences the risk of obesity in children and whether RYGB can mitigate these risks. Using a nonhuman primate model, the study will examine the physiological changes in offspring resulting from maternal RYGB and how it may reverse negative impacts caused by unhealthy diets during pregnancy. The research will provide insights into the potential benefits and risks of maternal weight loss surgery for both mothers and their children.
Who could benefit from this research
Good fit: Ideal candidates for this research include reproductive-age women who are considering or have undergone gastric bypass surgery and are pregnant or planning to become pregnant.
Not a fit: Patients who are not pregnant or do not have a history of obesity may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved health outcomes for both mothers and their children by identifying effective interventions for obesity prevention.
How similar studies have performed: Previous research has shown promising results regarding the impact of maternal weight loss on offspring health, but this specific approach using nonhuman primates is relatively novel.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Kievit, Paul — Oregon Health & Science University
- Study coordinator: Kievit, Paul
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.