How frustration affects drug-taking behavior
Official title: Frustration effects on drug taking
Funded at University of Texas Med Br Galveston · NIH-11064895 · Data updated 2026-11-12
This study looks at how feeling frustrated might affect teenagers' desire to use drugs by observing rat behavior, hoping to learn more about how early experiences with frustration can influence their choices around substance use.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Med Br Galveston NIH-funded |
| Lab location | 1 site (Galveston, United States) |
| Project start | April 15, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $400,000 |
| NIH project number | 5R01DA060221-02 |
| Project ID | NIH-11064895 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12 to 20 who may be at risk for substance use disorders.
✕Less likely to help
Patients outside the age range of 12 to 20 or those not experiencing issues related to substance use may not benefit from this research.
What this research studies
This research investigates the role of frustration in influencing motivation for drug use, particularly in adolescents. By studying rat behavior, the researchers aim to understand how frustration can either decrease or fail to decrease the motivation for substance use disorders. The project will utilize specific behavioral tests to measure how frustration impacts drug-seeking behavior and identify the neurobiological mechanisms involved. The findings could provide insights into how early life experiences shape individual responses to frustration and drug motivation.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating substance use disorders in adolescents.
How similar studies have gone: Previous research has shown that understanding behavioral responses to frustration can inform treatment approaches for substance use disorders, indicating that this area of study has potential for impactful findings.
Where this research is happening
-
University of Texas Med Br Galveston
Galveston, United States Active
Researchers
- Principal investigator: Green, Thomas Arthur — University of Texas Med Br Galveston
- Study coordinator: Green, Thomas Arthur
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.