How frailty affects the effectiveness of influenza vaccination in older adults
Frailty and Influenza Vaccination Among Older Adults
This study is looking at how frailty affects how well the flu vaccine works for older adults, especially veterans living in the community or in care centers, to help improve vaccination strategies for those who are more at risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Greater Los Angeles Healthcare System NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11044065 on NIH RePORTER |
What this research studies
This research investigates the relationship between frailty and the effectiveness of influenza vaccination among older adults, particularly focusing on community-dwelling Veterans and those in Community Living Centers. It aims to assess whether frailty, measured using the VA Frailty Index, influences vaccine effectiveness and outcomes after vaccination. By understanding these links, the research seeks to improve vaccination strategies for older adults who are at higher risk of severe outcomes from influenza. The study will utilize electronic assessments and analyze data to draw meaningful conclusions.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly Veterans, who may exhibit varying levels of frailty.
Not a fit: Patients who are not older adults or do not have any frailty concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccination strategies that enhance protection for older adults against influenza and its complications.
How similar studies have performed: Previous research has indicated that frailty can impact vaccine effectiveness, suggesting that this approach may yield valuable insights.
Where this research is happening
Los Angeles, United States
- VA Greater Los Angeles Healthcare System — Los Angeles, United States (Active)
Researchers
- Principal investigator: Seligman, Benjamin Joseph — VA Greater Los Angeles Healthcare System
- Study coordinator: Seligman, Benjamin Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.