How frailty affects liver transplant outcomes in older adults with liver cancer
The Impact of Frailty on Liver Transplant Outcomes in Older Adults with Hepatocellular Carcinoma
This study is looking at how being frail affects recovery and health after a liver transplant in older adults with liver cancer, aiming to find better ways to care for these patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11010004 on NIH RePORTER |
What this research studies
This research investigates the relationship between frailty and liver transplant outcomes specifically in older adults diagnosed with hepatocellular carcinoma. The study aims to apply principles of aging and geriatric care to better understand how frailty impacts recovery and overall health after liver transplantation. By leveraging a large cohort of patients, the research will analyze various factors, including cognitive health and functional abilities, to develop a comprehensive understanding of the challenges faced by older liver transplant recipients. The findings could lead to improved care strategies tailored for this vulnerable population.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who are diagnosed with hepatocellular carcinoma and are considering or awaiting liver transplantation.
Not a fit: Patients under the age of 65 or those without hepatocellular carcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the management and outcomes of liver transplantation for older adults, potentially leading to better recovery and quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the impact of aging and frailty on health outcomes in transplant populations, indicating that this approach is both relevant and potentially impactful.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Lai, Jennifer C. — University of California, San Francisco
- Study coordinator: Lai, Jennifer C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.