How frailty affects flu vaccination outcomes in older adults
Official title: Frailty and Influenza Vaccination Outcomes In A National Healthcare System
Funded at University of California Los Angeles · NIH-10912040 · Data updated 2026-11-12
This study is looking at how being frail affects how well the flu vaccine works for older adults aged 65 and up, with the goal of finding ways to better protect those who are more vulnerable.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 1, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $126,000 |
| NIH project number | 5R03AG082989-02 |
| Project ID | NIH-10912040 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 65 and older, particularly those who may be considered frail.
✕Less likely to help
Patients younger than 65 or those who are not frail may not receive direct benefits from this research.
What this research studies
This research investigates the relationship between frailty and the effectiveness of influenza vaccinations in older adults, particularly those aged 65 and over. By analyzing data from a national healthcare system, the study aims to understand how frailty may influence immune responses to the flu vaccine. Patients may benefit from insights that could lead to tailored vaccination strategies for frail individuals, enhancing their protection against influenza. The research will utilize electronic medical records and antibody titer measurements to assess vaccination outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccination strategies that enhance flu protection for frail older adults.
How similar studies have gone: Previous research has indicated that frailty can significantly impact health outcomes in older adults, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Seligman, Benjamin Joseph — University of California Los Angeles
- Study coordinator: Seligman, Benjamin Joseph
Related research
Other NIH-funded projects on the same topics.
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Frailty and Flu Vaccination in Older Adults
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-
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.