How food insecurity affects children's brain reward systems

The influence of food insecurity on reward neurobiology in children

NIH-funded research Pennsylvania State University, the · NIH-10470300

This study is looking at how not having enough food can affect the way kids and teens feel rewards and make choices, to help understand if it might lead to a higher chance of using drugs later on.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionPennsylvania State University, the NIH-funded
Lab location1 site (University Park, United States)
Project IDNIH-10470300 on NIH RePORTER

What this research studies

This research investigates the impact of food insecurity on the brain's reward systems in children and adolescents. It focuses on understanding how a lack of consistent access to food can influence neural processes related to reward and decision-making. By examining the effects of food deprivation and associated stress on brain development, the study aims to uncover potential links between food insecurity and increased risk for substance use. Participants may undergo assessments that evaluate their reward sensitivity and decision-making processes in relation to food and other rewards.

Who could benefit from this research

Good fit: Ideal candidates for this research are children and adolescents aged 0-21 who experience food insecurity, particularly those from rural areas.

Not a fit: Patients who do not experience food insecurity or are outside the age range of 0-21 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better interventions for children facing food insecurity, potentially reducing their risk of substance use and improving their overall mental health.

How similar studies have performed: Previous research has indicated that food deprivation can alter reward processing in both humans and animal models, suggesting that this approach has a foundation in established findings.

Where this research is happening

University Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.