How fewer children losing parents affects young people in Rakai, Uganda

Rakai Orphans in Communities

NIH-funded research Columbia University Health Sciences · NIH-11395988

This project looks at how declines in orphanhood from better HIV treatment affect HIV risk and social and economic outcomes for adolescents and young adults in Rakai.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11395988 on NIH RePORTER

What this research studies

If you are a young person in Rakai, this project follows how changes in parental death from HIV shape life chances as you move through adolescence and young adulthood. Researchers will measure exactly when children lost one or both parents and compare social, economic, and HIV-risk outcomes across groups who were orphaned at different ages. The team will use population data and local surveys, and may link clinic records and household information to understand long-term effects. Results are intended to inform programs and policies that support families and reduce HIV risk for youth.

Who could benefit from this research

Good fit: Ideal participants are adolescents and young adults from Rakai District, Uganda, including those who experienced parental death at different ages.

Not a fit: People who do not live in Rakai or whose families were never affected by HIV-related parental loss are unlikely to see direct benefits from this specific project.

Why it matters

Potential benefit: If successful, the work could help tailor services and policies to reduce HIV risk and improve social and economic supports for orphans and young people.

How similar studies have performed: Prior research has shown orphanhood is linked to worse outcomes, but using recent declines in orphanhood driven by expanded ART to study downstream effects is a newer approach.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.