How feedback from different brain areas affects sensory processing
Dynamic properties of neural circuits in the forebrain
['FUNDING_R01'] · MICHIGAN STATE UNIVERSITY · NIH-11059932
This study is looking at how different parts of the brain work together to process what we see and hear, using mice to learn more about how these connections affect our attention and awareness, which could help us understand conditions like autism and epilepsy better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MICHIGAN STATE UNIVERSITY (nih funded) |
| Locations | 1 site (EAST LANSING, UNITED STATES) |
| Trial ID | NIH-11059932 on ClinicalTrials.gov |
What this research studies
This research investigates the dynamic properties of neural circuits in the forebrain, particularly how feedback from various cortical areas influences sensory processing. By using mouse models, the study aims to understand the cellular and circuit mechanisms involved in this communication, which is crucial for cognitive functions like attention and awareness. The researchers will employ advanced techniques such as optogenetics to manipulate and observe these neural circuits in action. This work could provide insights into the underlying mechanisms of neuropsychiatric disorders like autism and epilepsy.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with autism spectrum disorder or other neuropsychiatric conditions that affect sensory processing.
Not a fit: Patients without neuropsychiatric disorders or those not experiencing sensory processing issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for neuropsychiatric disorders associated with sensory processing issues.
How similar studies have performed: Previous research has shown promising results in understanding neural circuits and their role in sensory processing, suggesting that this approach could yield valuable insights.
Where this research is happening
EAST LANSING, UNITED STATES
- MICHIGAN STATE UNIVERSITY — EAST LANSING, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CRANDALL, SHANE R — MICHIGAN STATE UNIVERSITY
- Study coordinator: CRANDALL, SHANE R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: autism spectral disorder, autism spectrum disorder, Autistic Disorder, autistic spectrum disorder