How fear learning changes brain networks
Fear learning-related reconfiguration of local and large-scale cortical networks
['FUNDING_CAREER'] · YALE UNIVERSITY · NIH-10894291
This study is looking at how learning to connect certain sights with feelings of fear changes the way different parts of the brain work together, especially in people who might be dealing with chronic stress, to help us better understand fear and anxiety disorders.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-10894291 on ClinicalTrials.gov |
What this research studies
This research investigates how learning to associate certain visual cues with fear responses alters the connectivity and function of brain networks, particularly in the neocortex. By using advanced imaging techniques, the study aims to uncover the changes in both local and larger-scale brain circuits that occur during fear learning. It focuses on understanding how chronic stress may affect these neural circuits and their ability to process sensory information. The findings could provide insights into the mechanisms of fear and anxiety disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing anxiety or fear-related disorders, particularly those affected by chronic stress.
Not a fit: Patients with no history of anxiety or fear-related disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for anxiety and fear-related disorders by enhancing our understanding of how fear is processed in the brain.
How similar studies have performed: Previous studies have shown success in understanding brain connectivity related to fear responses, making this research a continuation of established findings.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MOBERLY, ANDREW — YALE UNIVERSITY
- Study coordinator: MOBERLY, ANDREW
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.