How fatty acids affect ion channels that sense mechanical changes
Official title: Mechanosensitive Ion Channels Modulation by Membrane Composition
Funded at University of Texas Hlth Sci Ctr Houston · NIH-11097351 · Data updated 2026-11-12
This study looks at how certain fats in our diet affect tiny channels in our cells that help us feel touch and balance, using a small worm called C. elegans to learn more, with the hope of finding new ways to help people with related health issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | July 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $386,961 |
| NIH project number | 5R35GM153208-02 |
| Project ID | NIH-11097351 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing balance disorders or related neurological conditions.
✕Less likely to help
Patients with conditions unrelated to mechanosensitive ion channel dysfunction may not benefit from this research.
What this research studies
This research investigates how fatty acids, which are essential components of cell membranes, influence the function of mechanosensitive ion channels. These channels are crucial for converting mechanical stimuli into electrical signals, impacting various bodily functions such as balance and touch sensation. The study employs animal models, particularly C. elegans, to explore the effects of dietary fatty acids on these channels and their role in health and disease. By understanding these mechanisms, the research aims to develop new therapeutic strategies for conditions related to channel dysfunction.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for balance disorders and other conditions linked to mechanosensitive ion channel dysfunction.
How similar studies have gone: Previous research has shown promising results in modulating mechanosensitive ion channels using dietary interventions, indicating potential for success in this approach.
Where this research is happening
-
University of Texas Hlth Sci Ctr Houston
Houston, United States Active
Researchers
- Principal investigator: Vasquez, Valeria — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Vasquez, Valeria
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.