How fats and food affect how our bodies take in medicines and nutrients

Impact of lipids and food on oral compound absorption: mechanistic studies and modeling

NIH-funded research Northeastern University · NIH-11175967

This work helps us understand how fats in food and drug formulations change the way our bodies absorb important compounds like medicines and nutrients.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNortheastern University NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11175967 on NIH RePORTER

What this research studies

Our bodies absorb medicines, nutrients, and even toxins differently depending on the fats present in our food or in the drug itself. Currently, it's hard to predict how much of a substance our body will take in. This project aims to create better models to predict this absorption, which could make it easier to develop new medications and improve nutritional supplements. By understanding these mechanisms, we can design more effective oral treatments and better understand how food impacts our health.

Who could benefit from this research

Good fit: This foundational work does not directly involve patients, but future patients who take oral medications or supplements could benefit from improved drug formulations.

Not a fit: Patients seeking immediate treatment or direct participation in a clinical trial will not find direct benefit from this foundational research.

Why it matters

Potential benefit: If successful, this work could lead to more effective oral medications and nutritional supplements, making them work better for patients.

How similar studies have performed: The research team has already developed a preliminary modeling framework to predict the impact of lipids on oral compound absorption, providing a strong foundation for this project.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.