How fat tissue changes can lead to diabetes and other diseases
Official title: Mechanical Regulation of Adipose TissueFibrosis and Metabolic Disease
Funded at Boston University Medical Campus · NIH-11071318 · Data updated 2026-11-12
This study is looking at how changes in fat tissue can lead to problems like type 2 diabetes and heart issues, and it hopes to find new treatments that could help improve health for people dealing with obesity-related conditions.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | April 15, 2025 |
| Project end | April 14, 2027 |
| Funding year | 2025 |
| Award (this year) | $48,974 |
| NIH project number | 1F31DK139746-01A1 |
| Project ID | NIH-11071318 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing obesity-related conditions, particularly those with type 2 diabetes or metabolic syndrome.
✕Less likely to help
Patients who are not affected by obesity or related metabolic disorders may not receive any benefit from this research.
What this research studies
This research investigates how changes in fat tissue, particularly fibrosis, contribute to obesity-related diseases like type 2 diabetes and cardiovascular issues. It focuses on the role of the extracellular matrix surrounding fat cells and how it affects cell behavior and health. By understanding the mechanisms that drive fat tissue dysfunction, the research aims to identify potential therapies that could improve metabolic health. Patients may benefit from insights that could lead to new treatments targeting these pathways.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve metabolic health and reduce the risk of diseases associated with obesity.
How similar studies have gone: Previous research has shown promising results in understanding the role of the extracellular matrix in fat tissue health, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Boston University Medical Campus
Boston, United States Active
Researchers
- Principal investigator: Frosti, Cheyanne — Boston University Medical Campus
- Study coordinator: Frosti, Cheyanne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.