How farming lifestyles affect immune responses and allergies in children
Official title: Innate and Adaptive Immune Markers in Farming Lifestyle and Early Atopic Diseases
Funded at University of Rochester · NIH-11075814 · Data updated 2026-11-12
This study is looking at how growing up on farms might help protect kids from allergies and asthma by exposing them to different germs that can strengthen their immune systems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | April 7, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $406,683 |
| NIH project number | 5U19AI175113-03 |
| Project ID | NIH-11075814 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include infants and young children, particularly those with a family history of allergies or asthma.
✕Less likely to help
Patients who are older or do not have a history of allergic conditions may not benefit from this research.
What this research studies
This research investigates how living on farms may influence the development of allergies and asthma in children. It focuses on the role of microbial exposure in shaping the immune system from birth, particularly looking at how this exposure can lead to protective effects against allergic diseases. The study will analyze immune markers and responses in children with different backgrounds, aiming to understand the biological mechanisms behind these observations. By examining the relationship between farming lifestyles and immune function, the research seeks to identify potential strategies for preventing allergic conditions.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or managing allergies and asthma in children.
How similar studies have gone: Previous research has shown that farming lifestyles can reduce the risk of allergies, suggesting that this approach may yield valuable insights.
Where this research is happening
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University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Jarvinen-Seppo, Kirsi — University of Rochester
- Study coordinator: Jarvinen-Seppo, Kirsi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.