NIH-funded research R01 grant

How family eating and activity habits affect young children's weight

Official title: Role of energy balance behaviors in modifying biobehavioral risk factors for childhood obesity

Funded at University of Pennsylvania · NIH-11249654 · Data updated 2026-11-12

This project looks at whether young children's eating behaviors, activity, and family routines change weight over a year and can lessen genetic risk for obesity in kids ages 5–7 from low-resource families.

More Obesity research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startMarch 1, 2023
Project endDecember 31, 2027
Funding year2026
Award (this year)$551,488
NIH project number5R01DK134371-04
Project IDNIH-11249654 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are children aged 5–7 from low-resource households, especially those with strong appetite-driven eating behaviors or a family history of obesity.

Less likely to help

Children outside the 5–7 age range, families not in low-resource settings, or anyone seeking immediate treatment rather than observational research may not directly benefit from participation.

What this research studies

If your child participates, researchers will follow children aged 5 to 7 from low-resource families over one year to link eating behaviors, activity, and home routines with changes in weight and body fat. They will measure children's genetic risk using a genetic risk score and test appetite-related traits like how rewarding food is, eating speed, and eating when not hungry. The study combines behavioral measures, family environment information, and genetic data to see which behaviors modify obesity risk. Data collection will include repeated weight and adiposity measurements, standardized behavioral tasks, and caregiver surveys.

Why it matters

Potential benefit: If successful, the findings could point to specific, changeable family behaviors and routines that help lower children's obesity risk and guide targeted prevention efforts.

How similar studies have gone: Prior research has linked appetite traits and genetic risk to child weight, but combining genetic risk scores with detailed, prospective family behavior measures in low-resource families is a relatively new approach.

Where this research is happening

  • University of Pennsylvania
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Kral, Tanja V.e. — University of Pennsylvania
  • Study coordinator: Kral, Tanja V.e.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.