How family disadvantages affect young children's health during illnesses
Official title: Intergenerational disadvantage and pediatric health disparities in acute respiratory illness and diarrhea
Funded at University of Michigan at Ann Arbor · NIH-11170626 · Data updated 2026-11-12
This study looks at how ongoing challenges like poverty and discrimination affect the health of young children, especially when it comes to illnesses like colds and diarrhea, and it aims to understand how these issues impact their access to healthcare.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | August 15, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $669,100 |
| NIH project number | 5R01HD111446-02 |
| Project ID | NIH-11170626 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children under the age of five who come from families experiencing social and economic disadvantages.
✕Less likely to help
Patients who are not under five years old or who do not come from disadvantaged backgrounds may not benefit from this research.
What this research studies
This research investigates how ongoing social and economic disadvantages faced by families impact the health of children under five, particularly in relation to acute respiratory infections and diarrhea. By analyzing data from a longitudinal study, the research aims to understand the connection between these disadvantages and the healthcare services that children receive. It focuses on how factors like race, ethnicity, and community context influence both the incidence of these illnesses and access to timely medical care. The study seeks to fill a critical gap in understanding the long-term health disparities that arise from these intergenerational disadvantages.
Why it matters
Potential benefit: If successful, this research could lead to improved healthcare access and outcomes for disadvantaged children suffering from acute respiratory illnesses and diarrhea.
How similar studies have gone: Previous research has shown that addressing social determinants of health can significantly improve health outcomes in pediatric populations, suggesting that this approach has potential for success.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Treleaven, Emily — University of Michigan at Ann Arbor
- Study coordinator: Treleaven, Emily
Related research
Other NIH-funded projects on the same topics.
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PediCODE: A Biorepository and Consortium for CoDE - Congenital Diarrhea and Enteropathy
A nationwide effort to collect clinical data and patient-derived samples to uncover the genetic causes of congenital diarrhea and enteropathy and to build a resource that helps researchers study these diseases.
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PediCODE Consortium and Biobank for Congenital Diarrhea and Enteropathy
Creating a multi-center team and biobank to find genetic causes of congenital diarrhea and enteropathy in children and collect samples that can help future research.
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Mobile health tool to guide dehydration care for acute diarrhea across all ages
A mobile app uses AI to help people of all ages determine dehydration risk during acute diarrhea and guide rehydration decisions.
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Understanding how certain gut bacteria cause diarrhea in children and how it works in the gut lining
This project looks at how infections from ETEC and EPEC bacteria cause diarrhea, especially in children, and uses a mouse model and human-derived gut cell systems to uncover the underlying mechanisms.
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Targeting a gut transporter to help relieve constipation in CF and older adults
Aimed at helping people with cystic fibrosis and older adults who have chronic constipation by studying a gut transporter to improve intestinal fluid balance.
-
Targeting gut drug processing to prevent diarrhea from mycophenolate
This project tests whether using natural gut-acting compounds to boost a specific drug-clearing pathway in the lower intestine can reduce diarrhea caused by the transplant drug mycophenolate in people who take it.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.