How extreme heat and air pollution affect heart attacks in different people
Official title: Extreme Heat and Acute Myocardial Infarction: Effect Modifications by Sex, Medical History, and Air Pollution
Funded at Yale University · NIH-10919813 · Data updated 2026-11-12
This study is looking at how really hot weather and air pollution might lead to heart attacks, especially in different groups of people like young adults, older adults, and women, to see if things like gender, income, and health history make a difference in their risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 4, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $727,204 |
| NIH project number | 5R01HL169171-02 |
| Project ID | NIH-10919813 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include young adults aged 18-55 and older adults aged 75 and above, particularly those with pre-existing health conditions or those taking specific medications.
✕Less likely to help
Patients who are not affected by acute myocardial infarction or do not live in areas with significant air pollution or extreme heat may not benefit from this research.
What this research studies
This research investigates how extreme heat and air pollution may trigger acute myocardial infarction (AMI), particularly focusing on different groups such as young adults, older adults, and women. The study aims to understand if factors like sex, socioeconomic status, and medical history influence the risk of heart attacks during extreme weather conditions. By analyzing data from two large nationwide studies, researchers will explore the interactions between heat exposure and air pollution on heart health. Patients may be monitored for their health outcomes in relation to environmental factors.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies for heart attacks related to extreme heat and air pollution, ultimately saving lives.
How similar studies have gone: Previous research has shown that environmental factors like heat and air pollution can impact cardiovascular health, but this specific investigation into their combined effects is relatively novel.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Chen, Kai — Yale University
- Study coordinator: Chen, Kai
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.