How exposure to metals during pregnancy and early life affects lung health in children and adolescents
Effect of Perinatal Exposure to Metals on Lung Function Trajectories and Mitochondrial DNA Heteroplasmy from Childhood to Adolescence
This study is looking at how being around certain metals during pregnancy and early childhood might affect how well kids' lungs develop as they grow up, so we can find ways to keep their breathing healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11043404 on NIH RePORTER |
What this research studies
This research investigates the impact of exposure to environmental metals during pregnancy and infancy on lung function as children grow into adolescence. By examining how these exposures influence lung development, the study aims to identify critical periods when exposure may lead to adverse respiratory health outcomes. The research will utilize a longitudinal approach, tracking lung function over time to understand the long-term effects of metal exposure. This could help in developing strategies to mitigate risks associated with environmental toxins.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and adolescents who have been exposed to environmental metals during pregnancy or early life.
Not a fit: Patients who have not been exposed to environmental metals or who are outside the age range of 0 to 20 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention of respiratory diseases in children and adolescents.
How similar studies have performed: Previous research has shown that early life exposures can significantly impact health outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Rosa, Maria Jose — Icahn School of Medicine at Mount Sinai
- Study coordinator: Rosa, Maria Jose
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.