How exposure to chemical mixtures affects adolescent sleep and health
Pre- and postnatal chemical mixture exposure, adolescent sleep health, and allostatic load
['FUNDING_R01'] · UNIVERSITY OF LOUISVILLE · NIH-10928218
This study is looking at how being around certain chemicals before birth and during childhood might affect sleep and stress levels in teenagers, hoping to find ways to improve their health and sleep quality.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF LOUISVILLE (nih funded) |
| Locations | 1 site (LOUISVILLE, UNITED STATES) |
| Trial ID | NIH-10928218 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of early life exposure to chemical mixtures on sleep health and overall physiological stress in adolescents. It focuses on common environmental toxicants, such as phthalates and PFAS, which many pregnant individuals and children encounter through everyday products. By analyzing data from established pregnancy and birth cohorts, the study aims to determine if these exposures are linked to poor sleep and increased allostatic load during adolescence. The findings could help identify modifiable risk factors that affect sleep and health outcomes in young people.
Who could benefit from this research
Good fit: Ideal candidates for this research include adolescents aged 12-20 who may have been exposed to environmental toxicants during pregnancy or early childhood.
Not a fit: Patients who are not adolescents or who have not been exposed to the identified chemical mixtures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved sleep health and reduced physiological stress in adolescents, enhancing their overall well-being.
How similar studies have performed: Previous research has shown that environmental exposures can impact health outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
LOUISVILLE, UNITED STATES
- UNIVERSITY OF LOUISVILLE — LOUISVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SEARS, CLARA G — UNIVERSITY OF LOUISVILLE
- Study coordinator: SEARS, CLARA G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.