How exposure to certain chemicals during pregnancy affects women's heart and metabolic health over time
Exposure to phthalates and OP flame retardants and long-term maternal cardiovascular and metabolic health
['FUNDING_R01'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-11085129
This study is looking at how certain chemicals found in the environment might affect the heart and overall health of women before, during, and after pregnancy, so we can better understand their long-term health risks.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11085129 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of environmental chemicals, specifically phthalates and organophosphate flame retardants, on the cardiovascular and metabolic health of women during and after pregnancy. By analyzing urine samples from women before conception, during pregnancy, and in midlife, the study aims to uncover potential links between these chemical exposures and long-term health outcomes. The research focuses on understanding how these exposures may contribute to cardiovascular disease risk, which is a leading cause of death among women. Participants will be monitored for various health indicators, including blood pressure and metabolic markers, to assess the effects of these chemicals.
Who could benefit from this research
Good fit: Ideal candidates for this research include women who are pregnant, planning to become pregnant, or in midlife, especially those concerned about cardiovascular health.
Not a fit: Patients who are not women or those who are not in the reproductive age group may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for cardiovascular disease in women, particularly those who are pregnant or planning to conceive.
How similar studies have performed: Previous studies have shown associations between environmental exposures during pregnancy and adverse health outcomes, suggesting that this research builds on established findings but focuses on a less explored area.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MINGUEZ ALARCON, LIDIA — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: MINGUEZ ALARCON, LIDIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.