How exposure to bisphenol A during pregnancy affects infant brain and behavior

Environmental bisphenol exposure, infant brain and behavior: Human and animal models

NIH-funded research Columbia University Health Sciences · NIH-10461056

This study is looking at how being exposed to a chemical called BPA during pregnancy might affect babies' brain development and behavior, and it’s for expectant moms who want to know more about how their environment can impact their little ones.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10461056 on NIH RePORTER

What this research studies

This research investigates the impact of bisphenol A (BPA) exposure during pregnancy on the brain development and behavior of infants. It aims to understand both the direct effects of BPA on the infant's brain and the indirect effects through changes in mother-infant interactions. The study will utilize both human observations and animal models to explore these pathways, focusing on cognitive and social development in infants. By examining these relationships, the research seeks to uncover how BPA and its analogs may disrupt early neurobehavioral development.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant individuals who may have been exposed to bisphenol A or its analogs during pregnancy.

Not a fit: Patients who are not pregnant or whose infants are older than one year may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and prevention of neurodevelopmental issues in infants exposed to BPA.

How similar studies have performed: Previous research has shown that in utero exposure to endocrine-disrupting chemicals can negatively affect neurodevelopment, indicating that this approach has potential for significant findings.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.