NIH-funded research R01 grant

How expanding artery-opening (PCI) procedures affects disadvantaged versus other communities

Official title: Expansion of Percutaneous Coronary Intervention in Outpatient and Inpatient Settings: Quantifying the Differential Impact Between Disadvantaged and Non-Disadvantaged Communities

Funded at University of California, San Francisco · NIH-11135312 · Data updated 2026-11-12

This project looks at whether expanding artery-opening procedures (PCI) in hospitals and outpatient centers has helped or left behind people from disadvantaged communities with heart disease.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startJuly 1, 2016
Project endJune 30, 2027
Funding year2025
Award (this year)$599,947
NIH project number5R01HL134182-06
Project IDNIH-11135312 on NIH RePORTER

Who could benefit from this research

Could help

The people included are patients in California who had acute heart attacks or received PCI during the study years, especially those from low-income, uninsured, or racial/ethnic minority communities.

Less likely to help

People without coronary artery disease or those treated outside California are unlikely to be directly affected by this project.

What this research studies

From a patient perspective, researchers will use 10 years of individual patient records from California to compare who got PCI (stents/angioplasty) and how patients did afterward in disadvantaged versus non-disadvantaged communities. They will look at both procedures done in hospitals and those done in outpatient settings to see if growth in these services changed access, treatment, or outcomes for different groups. The team will link treatment patterns to community measures like income, insurance, and race to pinpoint system-level causes of disparities. No new clinic visits are required because the work uses existing medical records and administrative data.

Why it matters

Potential benefit: If successful, the work could identify ways to make access to PCI more equitable so disadvantaged patients get timely treatment and better outcomes.

How similar studies have gone: Previous research has shown unequal access to PCI across groups, but using PCI expansion over time to reveal system-level drivers of disparities is a relatively new approach.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Hsia, Renee Yuen-Jan — University of California, San Francisco
  • Study coordinator: Hsia, Renee Yuen-Jan

Related research

Other NIH-funded projects on the same topics.

  • Metasurface Optical Guidewire to Treat Coronary Artery Calcification

    A new optical guidewire technology aims to improve safety and effectiveness of coronary interventions in people with calcified arteries.

    NIH research Baylor College of Medicine · Houston, United States · NIH-11468164

  • Expansion of PCI use in different communities and who benefits

    Aims to understand how the growth of percutaneous coronary intervention (PCI) in outpatient and inpatient settings affects disadvantaged communities differently from non-disadvantaged ones.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11380038

  • Catheter that helps treat complex heart artery problems more safely

    A new catheter device is being developed to help doctors deliver stents in very hard-to-treat heart artery cases, potentially making complex procedures safer and more effective.

    NIH research Vantis Vascular INC · Kalamazoo, United States · NIH-11316492

  • Catheter that helps deliver stents in tough heart arteries

    A new guide-extension catheter system is being developed to safely reach and treat complex blockages in the heart’s blood vessels, especially where calcified and tortuous arteries make stent delivery hard.

    NIH research Vantis Vascular INC · Kalamazoo, United States · NIH-11261185

  • A new catheter designed to improve complex heart procedures

    This study is testing a new type of catheter designed to help doctors place stents more easily and safely in patients with severe heart artery blockages, especially when the arteries are tricky to navigate.

    NIH research Crossliner INC · Kalamazoo, United States · NIH-11011323

  • Using electronic health records to identify complications after heart procedures

    This study is working on a smart way to spot problems that can happen after a common heart procedure called PCI, using computer programs to look at health records, so that doctors can better keep you safe and provide the best care possible.

    NIH research Yale University · New Haven, United States · NIH-11001500

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.