How exercise affects fat tissue and metabolism during weight loss and regain in obesity
Exercise effects on adipose tissue morphology, metabolic function, and metabolic health with weight loss and weight regain in obesity
This study is looking at how exercising and eating less can help people with obesity improve their body fat and overall health, so if you're interested in how these changes can affect your weight and metabolism, this research might be for you!
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11095886 on NIH RePORTER |
What this research studies
This research investigates the combined effects of exercise and caloric restriction on fat tissue and metabolic health in individuals with obesity. It aims to understand how exercise influences the structure and function of adipose tissue, particularly in relation to weight loss and regain. By exploring the mechanisms behind these changes, the study seeks to optimize lifestyle interventions for better health outcomes. Participants may engage in exercise programs while undergoing dietary changes to assess the impacts on their body fat and metabolic function.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with obesity who are looking to lose weight and improve their metabolic health.
Not a fit: Patients who are not overweight or obese may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing obesity and its related health complications.
How similar studies have performed: Previous research has shown promising results regarding the benefits of combining exercise with caloric restriction for weight management and metabolic health.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Horowitz, Jeffrey F — University of Michigan at Ann Arbor
- Study coordinator: Horowitz, Jeffrey F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.