How exercise affects brain metabolism in older adults and those with Alzheimer's Disease
Acute exercise and the cerebral metabolic response in aging and Alzheimer's Disease
['FUNDING_R01'] · UNIVERSITY OF KANSAS MEDICAL CENTER · NIH-10799551
This study is looking at how exercising can affect brain health and blood markers in older adults, especially those with Alzheimer's Disease, to see how physical activity might help their brains work better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF KANSAS MEDICAL CENTER (nih funded) |
| Locations | 1 site (KANSAS CITY, UNITED STATES) |
| Trial ID | NIH-10799551 on ClinicalTrials.gov |
What this research studies
This research investigates how acute exercise influences brain metabolism and blood biomarkers in older adults, particularly those with Alzheimer's Disease. By comparing the responses of nondemented elderly individuals and those with Alzheimer's, the study aims to uncover the mechanisms behind the brain benefits of physical activity. Participants will engage in moderate to high-intensity exercise, and researchers will measure changes in brain glucose metabolism and related blood markers. The findings could help shape future clinical trials and exercise recommendations for aging populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults aged 65 and above, particularly those diagnosed with Alzheimer's Disease or showing early signs of cognitive decline.
Not a fit: Patients who are younger than 65 or do not have any cognitive impairments may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved exercise guidelines that enhance brain health and cognitive function in older adults and those with Alzheimer's Disease.
How similar studies have performed: Previous research has shown promising results regarding the benefits of exercise on brain health, but this specific comparison between aging and Alzheimer's Disease is relatively novel.
Where this research is happening
KANSAS CITY, UNITED STATES
- UNIVERSITY OF KANSAS MEDICAL CENTER — KANSAS CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MORRIS, JILL KATHLEEN — UNIVERSITY OF KANSAS MEDICAL CENTER
- Study coordinator: MORRIS, JILL KATHLEEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.