How exercise affects brain function and social skills in adolescents with autism

Effects of Exercise on Neurobiology, Social Cognition, and Systemic Inflammation in Autism

NIH-funded research University of Colorado Denver · NIH-11065899

This study is looking at how a 10-week exercise program can help improve brain function and social skills in young people aged 12-20 with autism, and it compares the effects of exercise to playing social games, all to see if being active can make a positive difference in their lives.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-11065899 on NIH RePORTER

What this research studies

This research investigates the impact of a 10-week exercise program on brain activity, social cognition, and inflammation levels in adolescents aged 12-20 with autism spectrum disorder (ASD). Participants will engage in exercise interventions compared to a social gaming control group to assess changes in brain function related to social understanding and emotional processing. The study aims to provide insights into how physical activity can improve social skills and reduce inflammation in this population, potentially enhancing their quality of life.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12-20 diagnosed with autism spectrum disorder.

Not a fit: Patients outside the age range of 12-20 or those without a diagnosis of autism spectrum disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective, low-cost interventions that improve social functioning and overall well-being for adolescents with autism.

How similar studies have performed: Preliminary studies have shown promise in using exercise to enhance social functioning in autistic individuals, indicating potential for success in this approach.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adolescent with autism spectrum disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.