How everyday stress affects heart health in middle-aged and older Black adults

Stress and Cardiovascular Risk Among Urban African American adults: A Multilevel, Mixed Methods Approach

NIH-funded research Wayne State University · NIH-11062461

This project looks at how daily stress, emotions, and habits relate to heart disease risk for urban African American adults.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWayne State University NIH-funded
Lab location1 site (Detroit, United States)
Project IDNIH-11062461 on NIH RePORTER

What this research studies

If you join, you'll complete brief daily surveys about stress, mood, and health behaviors during two separate year-long waves over two years. You'll also take part in interviews and come to a clinic visit for measurements and blood samples to look at inflammation and other biological signs. The study combines the daily reports, interviews, and lab measures to see which kinds of stress and reactions are linked to higher heart risk. Researchers will focus on middle-aged and older adults living in urban neighborhoods to better understand day-to-day experiences that matter most.

Who could benefit from this research

Good fit: Ideal candidates are African American adults living in urban areas (especially middle-aged and older adults) who can complete daily surveys and attend local clinic visits for interviews and blood draws.

Not a fit: People who are not African American, do not live in urban settings, or who cannot participate in repeated daily reporting and clinic visits may not directly benefit from this project.

Why it matters

Potential benefit: If successful, the work could point to specific stress-related behaviors and biological pathways to target in programs that reduce heart disease risk in African American communities.

How similar studies have performed: Previous research links stress and inflammation to heart disease, but detailed daily mixed-methods studies focused specifically on urban African American adults are relatively uncommon.

Where this research is happening

Detroit, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.