How epigenetic changes in primate brains relate to brain evolution
Comparative Epigenomics of Primate Brains
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA SANTA BARBARA · NIH-10873878
This study is looking at how changes in DNA can affect the way primate brains develop and function, helping us understand why different primates have different brain sizes and abilities.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA SANTA BARBARA (nih funded) |
| Locations | 1 site (SANTA BARBARA, UNITED STATES) |
| Trial ID | NIH-10873878 on ClinicalTrials.gov |
What this research studies
This research investigates the role of epigenetic modifications, specifically DNA methylation, in the evolution of primate brains. By comparing the epigenetic profiles of different primate species, the study aims to understand how these changes influence gene regulation and brain development. The research will focus on specific brain cell types and their unique DNA methylation patterns, which may provide insights into the evolutionary differences in brain size and function among primates. Through this approach, the study seeks to fill gaps in our understanding of how epigenetic evolution correlates with physical and functional changes in the brain.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with a keen interest in genetic and neurological studies, particularly those with conditions related to brain development.
Not a fit: Patients with conditions unrelated to brain development or genetic factors may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of brain development and evolution, potentially leading to new insights into neurological diseases.
How similar studies have performed: Previous research has shown promising results in understanding epigenetic changes in other species, suggesting that this comparative approach could yield valuable insights.
Where this research is happening
SANTA BARBARA, UNITED STATES
- UNIVERSITY OF CALIFORNIA SANTA BARBARA — SANTA BARBARA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YI, SOOJIN — UNIVERSITY OF CALIFORNIA SANTA BARBARA
- Study coordinator: YI, SOOJIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Candidate Disease Gene