How environmental stress affects gene processing in green algae

Regulation of co- and post-transcriptional pre-mRNA processing in response to environmental stress in green algae

['FUNDING_FELLOWSHIP'] · YALE UNIVERSITY · NIH-11066847

This study looks at how changes in temperature and exposure to arsenic affect the way a type of green algae, called Chlamydomonas reinhardtii, processes its genetic material, helping us understand how these tiny organisms adapt to their changing environments.

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorYALE UNIVERSITY (nih funded)
Locations1 site (NEW HAVEN, UNITED STATES)
Trial IDNIH-11066847 on ClinicalTrials.gov

What this research studies

This research investigates how environmental stressors, such as temperature changes and arsenic exposure, impact the processing of pre-mRNA in the green alga Chlamydomonas reinhardtii. By examining how these stressors influence gene expression and transcript diversity, the study aims to uncover the biological significance of these changes. The research utilizes laboratory cultivation of algae to quantify and evaluate the effects of stress on pre-mRNA processing, providing insights into the adaptability of aquatic organisms to changing environments.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include researchers and environmental scientists interested in aquatic biology and stress responses in organisms.

Not a fit: Patients with no interest in environmental science or those not involved in aquatic research may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of how aquatic organisms adapt to environmental stress, potentially informing conservation efforts and agricultural practices.

How similar studies have performed: While research on stress responses in algae is ongoing, this specific approach to studying pre-mRNA processing under environmental stress is relatively novel.

Where this research is happening

NEW HAVEN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.