How environmental stress affects gene processing in green algae
Official title: Regulation of co- and post-transcriptional pre-mRNA processing in response to environmental stress in green algae
Funded at Yale University · NIH-11066847 · Data updated 2026-11-12
This study looks at how changes in temperature and exposure to arsenic affect the way a type of green algae, called Chlamydomonas reinhardtii, processes its genetic material, helping us understand how these tiny organisms adapt to their changing environments.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | December 1, 2024 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $48,974 |
| NIH project number | 1F31ES037182-01 |
| Project ID | NIH-11066847 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include researchers and environmental scientists interested in aquatic biology and stress responses in organisms.
✕Less likely to help
Patients with no interest in environmental science or those not involved in aquatic research may not receive any benefit from this research.
What this research studies
This research investigates how environmental stressors, such as temperature changes and arsenic exposure, impact the processing of pre-mRNA in the green alga Chlamydomonas reinhardtii. By examining how these stressors influence gene expression and transcript diversity, the study aims to uncover the biological significance of these changes. The research utilizes laboratory cultivation of algae to quantify and evaluate the effects of stress on pre-mRNA processing, providing insights into the adaptability of aquatic organisms to changing environments.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of how aquatic organisms adapt to environmental stress, potentially informing conservation efforts and agricultural practices.
How similar studies have gone: While research on stress responses in algae is ongoing, this specific approach to studying pre-mRNA processing under environmental stress is relatively novel.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Shine, Morgan Ashleigh — Yale University
- Study coordinator: Shine, Morgan Ashleigh
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.