How environmental microplastics may worsen colorectal tumors
Official title: Mechanisms for environmental microplastics-enhanced colorectal tumor progression
Funded at University of New Mexico Health Scis Ctr · NIH-10982259 · Data updated 2026-11-12
This study is looking at how tiny bits of plastic in our environment might affect the growth of colorectal tumors, helping us understand if these plastics, which we can find in our food, water, and air, could increase the risk of cancer in our colon.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Mexico Health Scis Ctr NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project start | August 16, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $453,688 |
| NIH project number | 1R01ES035780-01A1 |
| Project ID | NIH-10982259 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with a history of colorectal issues or those concerned about the effects of environmental toxins on their health.
✕Less likely to help
Patients who do not have any gastrointestinal issues or are not exposed to microplastics may not benefit from this research.
What this research studies
This research investigates the impact of environmental microplastics on the progression of colorectal tumors. It focuses on how exposure to microplastics, which humans encounter through food, water, and air, can disrupt the normal function of colonic cells and potentially lead to cancer. The study will utilize advanced 3D cell culture techniques to better understand the cellular mechanisms involved in tumor growth and metastasis due to microplastic exposure. By examining these interactions, the research aims to uncover critical insights into the relationship between plastic pollution and colorectal cancer risk.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating colorectal cancer linked to environmental factors.
How similar studies have gone: While there is growing concern about microplastics and health, this specific investigation into their role in colorectal tumor progression is novel and has not been extensively studied.
Where this research is happening
-
University of New Mexico Health Scis Ctr
Albuquerque, United States Active
Researchers
- Principal investigator: Xue, Xiang — University of New Mexico Health Scis Ctr
- Study coordinator: Xue, Xiang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.