How environmental heat affects stroke outcomes in Alzheimer's disease patients
Impact of Environmental Stressors on Ischemic Stroke Outcome Inequities in Alzheimers Disease and Related Dementias
This study is looking at how hot weather and tough living conditions affect people with Alzheimer's and related dementias who have had a stroke, to see if those factors make their strokes worse and recovery harder, with the goal of helping to find better ways to care for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project ID | NIH-10977706 on NIH RePORTER |
What this research studies
This research investigates the impact of environmental heat and socioeconomic stressors on the outcomes of ischemic stroke in individuals with Alzheimer's disease (AD) and related dementias (ADRD). It aims to evaluate how living in neighborhoods with high heat vulnerability correlates with increased stroke severity and poorer recovery outcomes. By analyzing data from various neighborhoods, the study will assess the combined effects of heat exposure and socioeconomic factors on stroke morbidity and mortality in this vulnerable population. The findings could help identify at-risk patients and inform interventions to improve their care.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias who reside in socioeconomically disadvantaged neighborhoods prone to high temperatures.
Not a fit: Patients with Alzheimer's disease or related dementias living in areas not affected by significant heat exposure or socioeconomic stressors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted strategies that improve stroke outcomes for patients with Alzheimer's disease and related dementias living in high-risk environments.
How similar studies have performed: While the individual impacts of heat and socioeconomic stressors on stroke outcomes have been studied, this research is novel in its combined approach to evaluate their joint effects on patients with Alzheimer's disease and related dementias.
Where this research is happening
Manhasset, United States
- Feinstein Institute for Medical Research — Manhasset, United States (Active)
Researchers
- Principal investigator: Sanelli, Pina Christine — Feinstein Institute for Medical Research
- Study coordinator: Sanelli, Pina Christine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.