NIH-funded research NIH-funded research

How environmental factors affect cell signaling in plants

Official title: Osmotic Regulation of a Peptide Ligand-Mediated Signaling

Funded at Rutgers the State Univ of Nj Camden · NIH-10908525 · Data updated 2026-11-12

This study looks at how certain tiny proteins that help plants communicate are affected by changes in their environment, like when they experience water stress, using a common plant called Arabidopsis. By understanding how these proteins help control the openings in plant leaves that allow gas exchange, the researchers hope to learn more about how similar processes might relate to health issues in humans.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRutgers the State Univ of Nj Camden
NIH-funded
Lab location1 site (Camden, United States)
Project startSeptember 1, 2023
Project endJuly 31, 2028
Funding year2024
Award (this year)$391,354
NIH project number5R35GM151096-02
Project IDNIH-10908525 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for benefiting from this research include individuals with conditions linked to cell signaling abnormalities, such as certain cancers and metabolic disorders.

Less likely to help

Patients with conditions unrelated to cell signaling or those not affected by environmental factors may not receive direct benefits from this research.

What this research studies

This research investigates how peptide ligands, which are crucial for cell communication, are influenced by environmental conditions, particularly osmotic stress. By studying the model plant Arabidopsis thaliana, the research aims to understand the signaling pathways that regulate stomatal development, which are essential for gas exchange in plants. The project utilizes experimental techniques to analyze how these pathways adapt to changes in the environment, providing insights that could be relevant to human health and disease. The findings may help elucidate the mechanisms behind various diseases linked to dysregulated cell signaling.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for managing diseases related to cell signaling dysregulation in humans.

How similar studies have gone: Other research has shown success in understanding cell signaling pathways in plants, suggesting that this approach may yield valuable insights for human health.

Where this research is happening

  • Rutgers the State Univ of Nj Camden
    Camden, United States
    Active

Researchers

  • Principal investigator: Qi, Xingyun — Rutgers the State Univ of Nj Camden
  • Study coordinator: Qi, Xingyun

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.